Malignant Hyperthermia is a condition of severe high fever. After receiving anesthesia using anesthesia or muscle relaxants.

This causes the patient to have physical abnormalities from a high metabolic process. Which does not control calcium in the muscles. This is often seen in the news in various media, causing the death of people who undergo rhinoplasty or other procedures in surgical or dental clinics. 

Causes of allergic reaction to anesthesia

congenital

Dominant inherited disorders are เล่นบาคาร่า UFABET เว็บตรง ค่าคอมสูง expressed incompletely or may occur after gene changes. The risk can be divided according to the relatives of the patient, including:

• No. 1 Father, mother, children, siblings, chance of having this condition is 50%.

• 2nd place: nieces, aunts, uncles, etc., risk 25%

• 3rd rank, children of relatives, may occur up to 12.5 %

Allergic reaction to anesthesia

After a few hours of receiving anesthesia. The follow abnormalities often seen

• Muscles are continuously tensed without relaxation.

• Have higher than normal fever

• Sweating

• Rapid breathing

• Pulse and arrhythmia

• Skin turns dark green

• Urine flow is small and dark brown.

• Blood flows slowly or leaks from the body

• Low pressure

• Died

Diagnosis of anesthetic allergy

First, the doctor will take a history of the patient and examine them for symptoms. That indicate a risk of this condition. With additional laboratory tests.

Caffeine Halothane Contracture Test

• This is a standard method of cutting tissue for examination under anesthesia in the IVCT or In-Vtro Contraction Test laboratory. Currently, Thailand does not support this room.

Blood sampling for testing

• To study genetics by detecting gene changes with low sensitivity and specificity in the laboratory. When suspecte patients found suffer from anesthesia allergy.

This condition has similar features to severe hyperthyroidism. Complications of NMS include patients with tumors that secrete catecholamines.

Treatment of anesthetic allergy

Treat symptoms to reduce fever and help the patient breathe easily.

• Avoid or stop taking stimulants.

• Suspend surgery or complete surgical procedures possible.

• Give oxygen at a concentration of 100%, approximately twice the normal level.

• Give intravenous fluids

Specific treatment with Dantrolene

It is a powdered drug, combined with mannitol, mix in distilled water. Injected through a vein to reduce the severity that may cause harm to the body. If the patient following abnormal conditions

• Heart rate slows down

• Body temperature drops

• Muscle tension

• Abnormal carbon dioxide levels